Pesquisa sobre:
ACTIVATING TRANSCRIPTION FACTOR 6
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Activating Transcription Factor 6
Descritor
Espanhol
:
factor de transcripción activador 6
Descritor
Português
:
Fator 6 Ativador da Transcrição
Sinônimos
Inglês
:
ATF6 Transcription Factor
Transcription Factor, ATF6
Categoria:
D12.644.360.011
D12.776.260.108.061.968
D12.776.476.011
D12.776.930.127.061.968
Definição
Inglês
:
One of the
BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS
that is synthesized as a membrane-bound protein in the
ENDOPLASMIC RETICULUM
. In response to
endoplasmic reticulum stress
it translocates to the
GOLGI APPARATUS
. It is activated by PROTEASES and then moves to the
CELL NUCLEUS
to regulate GENETIC TRANSCRIPTION of GENES involved in the
unfolded protein response.
Nota Histórica
Inglês
:
2006(1997)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50762
Identificador Único:
D051702
Ocorrência na BVS
:
Similar:
DeCS